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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIN28
All Species:
6.06
Human Site:
S128
Identified Species:
11.11
UniProt:
Q9H9Z2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Z2
NP_078950.1
209
22743
S128
E
R
R
P
K
G
K
S
M
Q
K
R
R
S
K
Chimpanzee
Pan troglodytes
XP_513232
209
22865
N128
E
R
R
P
K
G
K
N
M
Q
K
R
R
S
K
Rhesus Macaque
Macaca mulatta
XP_001114640
143
15918
C73
R
R
S
K
G
D
R
C
Y
N
C
G
G
L
D
Dog
Lupus familis
XP_854985
206
22464
N124
E
R
R
P
K
G
K
N
M
Q
K
R
R
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3Y3
209
22701
N128
E
R
R
P
K
G
K
N
M
Q
K
R
R
S
K
Rat
Rattus norvegicus
P62961
322
35711
H142
K
Y
A
A
D
R
N
H
Y
R
R
Y
P
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506004
274
29355
M138
E
R
R
P
K
G
K
M
L
Q
K
R
K
P
K
Chicken
Gallus gallus
Q45KJ5
202
22071
S122
E
R
R
P
K
S
K
S
L
Q
K
R
R
S
K
Frog
Xenopus laevis
Q8JHC4
195
21688
G122
E
R
R
P
K
V
K
G
Q
Q
K
R
R
Q
R
Zebra Danio
Brachydanio rerio
Q803L0
202
21867
Q122
E
K
K
P
K
G
T
Q
K
R
R
S
K
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRN5
195
21575
R120
T
Y
R
P
R
I
N
R
R
T
R
R
M
R
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P92186
227
25447
L134
K
G
S
R
I
H
P
L
G
R
K
K
A
V
S
Sea Urchin
Strong. purpuratus
XP_792032
234
25286
Y144
K
R
R
L
R
P
K
Y
R
R
T
A
N
R
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
65.5
95.2
N.A.
96.6
20.8
N.A.
53.2
80.8
62.6
66.9
N.A.
34.9
N.A.
26.4
33.7
Protein Similarity:
100
98.5
67.4
96.6
N.A.
98.5
34.4
N.A.
60.2
87
74.1
79.4
N.A.
47.8
N.A.
44
47
P-Site Identity:
100
93.3
6.6
93.3
N.A.
93.3
0
N.A.
73.3
86.6
66.6
26.6
N.A.
20
N.A.
6.6
20
P-Site Similarity:
100
100
13.3
100
N.A.
100
26.6
N.A.
86.6
93.3
73.3
60
N.A.
33.3
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
16
% C
% Asp:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
16
% D
% Glu:
62
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
47
0
8
8
0
0
8
8
8
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
24
8
8
8
62
0
62
0
8
0
62
8
16
0
47
% K
% Leu:
0
0
0
8
0
0
0
8
16
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
8
31
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
16
24
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
70
0
8
8
0
0
0
0
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
0
8
8
54
0
0
0
8
0
% Q
% Arg:
8
70
70
8
16
8
8
8
16
31
24
62
47
24
16
% R
% Ser:
0
0
16
0
0
8
0
16
0
0
0
8
0
39
8
% S
% Thr:
8
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
0
0
0
0
0
8
16
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _